Some work I performed as a scientist at IBM Almaden Research Center: A degradable polymeric mixed-micelle system based on amphiphilic mPEG-b-polycarbonate
diblock copolymers was developed. This mussel-inspired polymer design
features catechol side chains to which the anticancer drug doxorubicin
(DOX) can be covalently conjugated as pH-sensitive p-quinoneimines via a mechanism that mimics the Raper–Mason pathway of mammalian melanogenesis.
Article link: http://pubs.acs.org/doi/abs/10.1021/acs.macromol.5b02784
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